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Regulated autocrine growth of CHO cells

✍ Scribed by Noelle-Anne Sunstrom; Sugiyono; Sybille Hunt; Charles Bailey; Masood Baig; Merilyn Sleigh; Peter Gray


Book ID
110259948
Publisher
Springer
Year
2000
Tongue
English
Weight
123 KB
Volume
34
Category
Article
ISSN
0920-9069

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Chinese Hamster Ovary (CHO) cells are widely used for the large scale production of recombinant biopharmaceuticals. Growth of the CHO-K1 cell line has been demonstrated in serum-free medium containing insulin, transferrin and selenium. In an attempt to get autocrine growth in protein-free medium, DN