Regular and relayed heteronuclear correlations by a single two-dimensional experiment involving an RF gradient

✍ Scribed by D. Canet; J. Brondeau; F. Montigny; F. Humbert

• Publisher: John Wiley and Sons
• Year: 1992
• Tongue: English
• Weight: 345 KB
• Volume: 30
• Category: Article
• ISSN: 0749-1581
• DOI: 10.1002/mrc.1260300611

✦ Synopsis

Abstract

In order to achieve a better suppression of signals arising from protons non‐bonded to the considered heteronucleus, two (π/4) proton pulses are used in the HMQC sequence: one, at the very beginning, replaces the classical (π/2) pulse and the other is at the end of the sequence. In addition, a spin‐lock purging period improves the elimination process. This novel sequence is shown to provide the conventional heteronuclear correlations and, in addition, relayed homonuclear (proton–proton) correlations. A simple methodology capable of sorting out both types of correlations is proposed. However, this procedure entails a sensitivity loss by a factor of two.