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Regiospecific lithiation of phenoxazine ortho to the oxygen atom. Synthesis of 4-mono- and 4,6-disubstituted phenoxazine derivatives

โœ Scribed by Antonio, Yulia; Barrera, Patricia; Contreras, Olga; Franco, Fidencio; Galeazzi, Edvige; Garcia, Josefina; Greenhouse, Robert; Guzman, Angel; Velarde, Esperanza; Muchowski, Joseph M.


Book ID
127360116
Publisher
American Chemical Society
Year
1989
Tongue
English
Weight
948 KB
Volume
54
Category
Article
ISSN
0022-3263

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Lithiated Azafulvenes by Halogen/Metal I
โœ Brian L. Bray; Petr Hess; Joseph M. Muchowski; Markus E. Scheller ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› John Wiley and Sons ๐ŸŒ German โš– 244 KB

The first known lithiated 1-azafulvene derivatives were generated by low-temperature halogen/metal interchange, with r-BuLi, from the corresponding brominated 6-diisopropylamino compounds 3b and 12. These Li species reacted with sundry electrophilic reagents to give products which, on basic hydrolys