Selective Bromination of 4,5-Dimethylthi
β
Mouaffak Al Hariri; Olivier Galley; FΓ©lix Pautet; Houda Fillion
π
Article
π
1998
π
John Wiley and Sons
π
English
β 313 KB
Radical bromination of 4,5-dimethylthiazole (1) was carried out using different stoichiometries of N-bromosuccinimide in the presence of 2,2Π-azobisisobutyronitrile. Mono-, tri-and tetrabromo compounds 2, 5, and 6 were obtained in good yields with regioselectivity while the dibromo derivatives 3 and