Regioselectivity of ring-opening reactions of optically active N-acetyl-2-methoxycarbonylaziridine
✍ Scribed by Maria Bucciarelli; Arrigo Forni; Irene Moretti; Fabio Prati; Giovanni Torre
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 455 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0957-4166
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📜 SIMILAR VOLUMES
## Abstract The synthesis of a series of optically active __N__‐acetyl butenoates **3–5** is described using a facile methodology. These butenoates undergo cyclization to the corresponding __N__‐acetyl‐2‐alkyl‐pyrrolin‐4‐ones **6,7** retaining their stereochemical integrity. The structure of the ne
## Abstract Diethyl or dimethyl benzyloxycarbonylaminomalonate was reacted with ring substituted benzyl halides and the resulting arylalkyl derivatives (**3** to **6**) half‐saponified to the DL‐monoacid‐monoesters (**7** to **10**). Decarboxylation by refluxing in dioxane afforded the N‐benzyl oxy