Regioselectivity in the Nucleophile Trapping of Arynes: The Electronic and Steric Effects of Nucleophiles and Substituents
β Scribed by Karmakar, Rajdip; Yun, Sang Young; Wang, Kung-Pern; Lee, Daesung
- Book ID
- 127212247
- Publisher
- American Chemical Society
- Year
- 2013
- Tongue
- English
- Weight
- 683 KB
- Volume
- 16
- Category
- Article
- ISSN
- 1523-7060
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S~~~WZY: A high regioselectivity has been observed in the palladia catalyzed allylation of "soft" nucleophiles (pentane-2,4-dione and 4-hydroxy-6methyl-2pyrone) when both allylic termini have the same steric requirements and different electronic features. The palladium catalyzed allylation of proto
The stereocontrolled synthesis of tricyclic compounds through an efficient and highly regioselective 5-exo-trig palladium catalyzed biscyclization process is reported, starting from compounds 1. The 6-endo competing cyclization can also be the only pathway leading to transoctahydrophenanthrene. In t