Regioselective Reduction of 2,4-Diacylpyrroles and the Synthesis of a 2,4-Divinylpyrrole

✍ Scribed by Yan Li; David Dolphin

• Publisher: John Wiley and Sons
• Year: 2009
• Tongue: English
• Weight: 325 KB
• Volume: 2009
• Category: Article
• ISSN: 1434-193X
• DOI: 10.1002/ejoc.200900331

✦ Synopsis

Abstract

Reduction of 2,4‐diacylpyrroles followed by dehydration to prepare the divinylpyrroles has been studied. The N‐phenylsulfonyl group exhibited directing ability at the 4‐position during the reduction of 2,4‐diacylpyrrole and complete regioselectivity was achieved for formations of the 2‐ and 4‐carbinols; several new derivatives, including 2,4‐divinylpyrrole, have been prepared.(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)