Regioselective openings of 2,3-epoxy acids with organocuprates
β Scribed by J.Michael Chong; K.Barry Sharpless
- Book ID
- 104226839
- Publisher
- Elsevier Science
- Year
- 1985
- Tongue
- French
- Weight
- 227 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0040-4039
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β¦ Synopsis
Lithium organocuprates react with 3-alkyl-2,3-epoxy acids (glycidic acids) to afford the products of ring-opening in good yield.
The regiochemistry of ringopening is dependent on the stereochemistry of the epoxy acid.
π SIMILAR VOLUMES
Lithium borohydride reduction of 2,3-epoxy alcohols was shown to yield 1,2-diols in high regioselectivity with the aid of titanium tetraisopropoxide in benzene solution.
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