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Regioselective N-alkylation for the synthesis of novel aminotriazolophanes

✍ Scribed by M. S. Chande; Meera H. Uchil; P. A. Barve

Book ID: 102846365
Publisher: John Wiley and Sons
Year: 2006
Tongue: English
Weight: 641 KB
Volume: 17
Category: Article
ISSN: 1042-7163
DOI: 10.1002/hc.20211

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✦ Synopsis

Abstract

Regioselective synthesis of macrocycles, incorporating 3‐oxo‐4‐amino‐1,2,4‐triazole derivatives, has been achieved by reactions involving N‐alkylation, utilizing appropriate 1, ω ‐dihaloalkanes in the presence of metal hydroxide. © 2006 Wiley Periodicals, Inc. Heteroatom Chem 17:329–336, 2006; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20211

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