Regioselective metalation of thiazolo[5,4-b]pyridines
β Scribed by Axel Couture; Eric Huguerre; Pierre Grandclaudon
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- French
- Weight
- 131 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0040-4039
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β¦ Synopsis
Lithiation with LDA of thiazolo[5,4-blpyridines occurs regioselectively on the position in the pyridine ring.
π SIMILAR VOLUMES
## Abstract magnified image A oneβstep synthesis of thiazolo[5,4β__b__]pyridines from an appropriately substituted chloronitropyridine and thioamide, or thiourea, is presented. In particular, the reaction was used to prepare a large number of 6βnitrothiazolo[5,4β__b__]pyridine derivatives, bearing
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