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Regioselective heteroannelation in quinazolin-4-one derivatives. Synthesis of 2,5-dioxo-1,2,4,5-tetrahydropyrrolo[1,2-a]quinazoline-3-carbonitriles

✍ Scribed by Yulian M. Volovenko; Elizaveta V. Resnyanskaya


Book ID
119767987
Publisher
Royal Society of Chemistry
Year
2002
Tongue
English
Weight
87 KB
Volume
12
Category
Article
ISSN
0959-9436

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## Abstract A series of 2‐[mercapto(cyano)methylene]‐1,2,3,4‐tetrahydroquinazolin‐4‐ones and 2‐amino‐4‐methylpyrazolo[1,5‐a]quinazolin‐5(4__H__)‐one were prepared from 2‐cyanomethylquinazolin‐4(3__H__)‐ones __via__ α‐bromo derivatives 4 and amide oxime 8, respectively. The new compounds have been c