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Regioselective functionalization. .beta. Substituent effects on the regioselectivity of Baeyer-Villiger oxidations of 3-substituted 2-azabicyclo[2.2.2]octan-5-ones (isoquinuclidin-5-ones)

✍ Scribed by Krow, Grant R.; Johnson, Constance A.; Guare, James P.; Kubrak, Dennis; Henz, Kenneth J.; Shaw, Donald A.; Szczepanski, Steven W.; Carey, James T.


Book ID
118221840
Publisher
American Chemical Society
Year
1982
Tongue
English
Weight
731 KB
Volume
47
Category
Article
ISSN
0022-3263

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Polar substituent effects on the aromatic ring emerge in the regioselectivity of the di-n-methane rearrangement of the title compounds when they possess the structural feature of including the bridgehead carbon in a saturated ring; the importance of the environment at the bridgehead carbon is pointe