Regioselective alkanoylation of cyclodextrins
โ Scribed by Donghong Yu; Kim Steffensen; Jesper Tranholm; Anne Louise Nielsen; Reinhard Wimmer; Kim Lambertsen Larsen
- Publisher
- Springer Netherlands
- Year
- 2007
- Tongue
- English
- Weight
- 323 KB
- Volume
- 57
- Category
- Article
- ISSN
- 0923-0750
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Regioselective reactions of 1-(1-naphthyl)ethyl isocyanate (NEIC) with beta-cyclodextrin (beta-CD) were studied with and without NaH activation of beta-CD in N,N-dimethylformamide (DMF) and pyridine. All six possible monosubstituted CD products were separated and characterized by proton NMR. Primary
A new and convenient procedure has been developed for the regioselective tosylation of a C-2 hydroxyl group of cyclodextrins via cyclic tin intermediate. Cyclodextrin(CD)s (1) have attracted current interests as enzyme mimics' and chemical modification of CDs with various functional groups has been
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