Treatment of optically active 2,3-epoxyalcohols with trialkylaluminum reagents followed by periodate cleavage constitutes a convenient synthesis of a-chiral aldehyde derivatives, especially when the branching alkyl group is methyl. We recently required a convenient source of either 1,2-diol 2 or 1,3
Regioselective addition reactions of organometallic reagents with 3-benzylidene heterocyclic imines leading to the synthesis of pyrrolizidines
β Scribed by Hua, Duy H.; Bensoussan, Didier; Bravo, Ana A.
- Book ID
- 127071231
- Publisher
- American Chemical Society
- Year
- 1989
- Tongue
- English
- Weight
- 597 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0022-3263
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The 1,3-cycloaddition reaction of aroyl-substituted heterocyclic ketene aminals with nitrile imines proceeded via a nucleophilic addition followed by intramolecular cyclocondensation to give fully substituted pyrazole derivatives.