Reaction of aroyl-substituted heterocyclic ketene aminals with nitrile imines: an efficient synthesis of fully substituted pyrazoles and evidence of nucleophilic addition of enamines to 1,3-dipoles

✍ Scribed by Bo Liu; Mei-Xiang Wang; Zhi-Tang Huang

• Book ID: 104262309
• Publisher: Elsevier Science
• Year: 1999
• Tongue: French
• Weight: 214 KB
• Volume: 40
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(99)01528-2

✦ Synopsis

The 1,3-cycloaddition reaction of aroyl-substituted heterocyclic ketene aminals with nitrile imines proceeded via a nucleophilic addition followed by intramolecular cyclocondensation to give fully substituted pyrazole derivatives.