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Regioselective acylation of several polyhydroxylated natural compounds by Candida antarctica lipase B

✍ Scribed by Teng, Rong-Wei; Bui, Thi-Kim-Anh; McManus, David; Armstrong, David; Mau, Shaio-Lim; Bacic, Antony

Book ID: 126150348
Publisher: Informa plc
Year: 2005
Tongue: English
Weight: 115 KB
Volume: 23
Category: Article
ISSN: 1024-2422
DOI: 10.1080/1024220500132508

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## Abstract Candida antarctica __lipase B (CAL‐B) catalyzes the regioselective acylation of natural thymidine with oxime esters and also the regioselective acylation of an analogue, 3′,5′‐diamino‐3′,5′‐dideoxythymidine with nonactivated esters. In both cases, acylation favors the less hindered 5′‐p