๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Regional circadian variation of acetylcholine muscarinic receptors in the rat brain

โœ Scribed by Suzanne B. Por; Stephen C. Bondy


Publisher
John Wiley and Sons
Year
1981
Tongue
English
Weight
239 KB
Volume
6
Category
Article
ISSN
0360-4012

No coin nor oath required. For personal study only.

โœฆ Synopsis


Abstract

The level of binding of a labeled acetylcholine muscarinic antagonist (quinuclidinyl benzilate) to different cerebral membranes has been measured. Of the regions examined, circadian rhythmicity of binding could only be detected significantly in the hippocampus and the hypothalamus and not in the cerebral cortex, striatum, or cerebellum.


๐Ÿ“œ SIMILAR VOLUMES


MUSCARINIC ACETYLCHOLINE RECEPTOR SUBTYP
โœ PHILLIP A. WACKYM; CAROLINE T. CHEN; AKIRA ISHIYAMA; ROBERT M. PETTIS; IVรN A. L ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 493 KB

The expression of the five muscarinic acetylcholine receptor (mAChR) subtypes (m1-m5) in the vestibular end-organs and in the primary afferent vestibular ganglia of the human and rat was studied using RT-PCR from the two tissue populations from both species. In the human, although all five mAChR sub

Effects of cochlear ablation on muscarin
โœ Yong-Ming Jin; Donald A. Godfrey ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 332 KB ๐Ÿ‘ 2 views

Cholinergic synapses in the cochlear nucleus (CN) have been reported to modulate spontaneous activity via muscarinic acetylcholine receptors. In this study, muscarinic receptor binding was measured as specific binding of 1-[N-methyl-(3)H]scopolamine in CN regions of control rats and 7 days, 1 month,

Inhibition of regional brain acetylcholi
โœ Dr. Jerry J. Buccafusco ๐Ÿ“‚ Article ๐Ÿ“… 1984 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 477 KB ๐Ÿ‘ 1 views

Recent studies in this laboratory have demonstrated that clonidine, a centrally acting antihypertensive drug, can inhibit the function of central cholinergic neurons. We have also provided evidence for enhanced brain cholinergic activity in the spontaneously hypertensive rat (SHR). The purpose of th

Modulation of long-term potentiation by
โœ Le Luo; Wei-Heng Chen; Ming Wang; Da-Miao Zhu; Jia-Qi She; Di-Yun Ruan ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 164 KB

The roles of the muscarinic acetylcholine (ACh) receptors (mAChRs) in long-term potentiation (LTP) at many areas of the central nervous system including the hippocampus, have been extensively studied. However, not much is known about the modulation of LTP through individual subtypes of mAChR (M(1)-M

Pharmacokinetics of anticholinergic drug
โœ Emi Nakashima; Junko Ishizaki; Masami Takeda; Ryo Matsushita; Koichi Yokogawa; F ๐Ÿ“‚ Article ๐Ÿ“… 1993 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 653 KB

We studied the effects of experimental diabetes on the pharmacokinetics of biperiden (BP) and scopolamine (SP) and brain muscarinic receptor alterations in rats after the injection of streptozotocin (STZ) (60mg kg-' i.v.). The serum levels of BP and SP differed significantly between the rats 14 week

Identification and localization of musca
โœ Fischer, Andy J.; McKinnon, Lise A.; Nathanson, Neil M.; Stell, William K. ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 818 KB

The purpose of this study was to characterize the distribution of muscarinic acetylcholine receptors (mAChRs) in the ocular tissues of hatched chicks. In the chick, different isoforms of these receptors have been detected in the brain, heart, and retina, and mAChRs in ocular tissues have been implic