Regional chromosome localization of human papillomavirus intergration sites near fragile sites, oncogenes, and cancer chromosome breakpoints
✍ Scribed by Linda A. Cannizzaro; Matthias Dürst; Michael J. Mendez; Barbara K. Hecht; Frederick Hecht
- Book ID
- 119103789
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- English
- Weight
- 288 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0165-4608
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
The HST/FGFK gene, a member of the fibroblast growth factor gene family and a protooncogene, is localized on chromosomal band I I q I 3. Genes in this region are frequently involved in hematopoietic and solid tumors. Here we show that the HST gene lies telomeric to the BCL / gene, the t( I I ; I4)(q
## Abstract Common fragile sites (CFSs) are expressed as chromosome gaps in cells of different species including human and mouse as a result of the inhibition of DNA replication. They may serve as hot spots for DNA breakage in processes such as tumorigenesis and chromosome evolution. Using multicol