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Regional Cerebrovascular Transport of Leucine as Measured by the In Situ Brain Perfusion Technique

โœ Scribed by Smith, Quentin R.; Takasato, Yoshio; Sweeney, Daniel J.; Rapoport, Stanley I.

Book ID
109869619
Publisher
Nature Publishing Group
Year
1985
Tongue
English
Weight
788 KB
Volume
5
Category
Article
ISSN
0271-678X

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To characterize pentazocine (PTZ) transport across the blood-brain barrier (BBB), the cerebrovascular permeability-surface area product (PS(inf)) of PTZ was determined by a well-established in situ rat brain perfusion technique. The uptake kinetics of PTZ by the rat brain exhibited saturability, whi