Regiocontrolled synthesis of bicyclo[3.2.1]octane derivatives by cuprate addition and intramolecular acylation
✍ Scribed by Anthony J. Pearson
- Book ID
- 107858250
- Publisher
- Elsevier Science
- Year
- 1980
- Tongue
- French
- Weight
- 179 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0040-4039
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## Abstract The synthesis of 1‐bicyclo[3.2.2]nonene **(2)** and of 1 (7)‐bicyclo [3.2.2]nonene **(3)**, two isomeric bridged (__E__)‐cycloheptenes, by intramolecular __Wittig__ reaction is described. These ‘__Bredt__ olefins’ could not be isolated, but dimerized rapidly. In both cases, the main pro
## Abstract The synthesis of the enantiomerically pure, bridgehead‐functionalized bicyclo[3.2.1]octanes 11 and 16, containing a conformationally fixed trihydroxypropyl (aminodihydroxypropyl) unit, as well as the X‐ray structure of 11 are described. These compounds are of interest as sugar surrogate