Regio- and Stereoselective Synthesis of Cyclopentenones: Intermolecular Pseudo-Pauson–Khand Cyclization
✍ Scribed by Prof. José Barluenga; Ana Álvarez-Fernández; Dr. Ángel L. Suárez-Sobrino; Prof. Miguel Tomás
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 370 KB
- Volume
- 124
- Category
- Article
- ISSN
- 0044-8249
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## Abstract For Abstract see ChemInform Abstract in Full Text.
## Abstract For Abstract see ChemInform Abstract in Full Text.
Thc carbacyclin precursors 11, 17, 18 have been prepared from the en-ynes 10, 15, 16 by cobalt-mediated cyclization (Pauson-Khand reaction) with varying degrees of diastereoselectiviiy. Prostacyclin (1 a) shows outstanding effects on the mammalian organism, in particular with respect to vasodilatio
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