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Regio- and stereoselective synthesis of aminoalkadienoic acids from substituted derivatives of thiophene

✍ Scribed by E. P. Zakharov; Ya. L. Gol'dfarb; F. M. Stoyanovich


Book ID
112445271
Publisher
Springer
Year
1982
Tongue
English
Weight
50 KB
Volume
31
Category
Article
ISSN
1573-9171

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A regio- and stereoselective synthesis o
✍ Philippe Bayard; LΓ©on Ghosez πŸ“‚ Article πŸ“… 1988 πŸ› Elsevier Science 🌐 French βš– 177 KB

The new activated 2-aza-1,3-dienes 1 are readily prepared by acylation of N-tri-methylsilylimines 3. They react with electrophilic olefins to yield substituted piperidones 4 \_ and 6 with high diastereoselectivity.