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Regio- and stereoselective synthesis of 1,4-dihydropyridines by way of an intramolecular interaction of a thiocarbonyl or carbonyl with a pyridinium nucleus

✍ Scribed by Shinji Yamada; Tomoko Misono; Mayumi Ichikawa; Chisako Morita


Book ID
108371379
Publisher
Elsevier Science
Year
2001
Tongue
French
Weight
242 KB
Volume
57
Category
Article
ISSN
0040-4020

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πŸ“œ SIMILAR VOLUMES


Stereoselective synthesis of 1,2- and 1,
✍ Shinji Yamada; Momoe Saitoh; Tomoko Misono πŸ“‚ Article πŸ“… 2002 πŸ› Elsevier Science 🌐 French βš– 115 KB

Selective shielding of one side of the pyridinium face by way of intramolecular cation-p complex formation enabled nucleophiles to attack the pyridinium ring from the non-shielded side. As a result, 1,2-and 1,4-dihydropyridines were formed in good stereoselectivities. 1 H NMR analysis and ab initio