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Regio- and Stereoselective Ring-Opening Reaction of Chiral Aziridines: A Facile Synthesis of Chiral β-Amino Alcohols

✍ Scribed by Higashiyama, Kimio; Matsumura, Masataka; Kojima, Hiroshi; Yamauchi, Takayasu

Book ID
120455129
Publisher
Japan Institute of Heterocyclic Chemistry
Year
2009
Tongue
English
Weight
316 KB
Volume
78
Category
Article
ISSN
0385-5414

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📜 SIMILAR VOLUMES

A facile synthesis of chiral N-protected
A facile synthesis of chiral N-protected β-amino alcohols.
✍ Marc Rodriguez; Muriel Llinares; Sylvie Doulut; Annie Heitz; Jean Martinez 📂 Article 📅 1991 🏛 Elsevier Science 🌐 French ⚖ 211 KB

Chiral N-protected p-amino alcohols are easily obtained by NaB& reduction of mixed anhydndes of N-protected a-ammo acids m an organic/aqueous medium. The alcohols obtamed from side chain or main chain reduction of N-protected asparhc acid are converted in good yields into lactones.