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Regio- and Stereoselective Cross-Coupling of Substituted Olefins and Imines. A Convergent Stereoselective Synthesis of Saturated 1,5-Aminoalcohols and Substituted Piperidines

✍ Scribed by Takahashi, Masayuki; Micalizio, Glenn C.


Book ID
121875776
Publisher
American Chemical Society
Year
2007
Tongue
English
Weight
368 KB
Volume
129
Category
Article
ISSN
0002-7863

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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.

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The new activated 2-aza-1,3-dienes 1 are readily prepared by acylation of N-tri-methylsilylimines 3. They react with electrophilic olefins to yield substituted piperidones 4 \_ and 6 with high diastereoselectivity.