Regio- and stereodirectivity in the reactions of isoquinolinium ylides with unsaturated nitriles
β Scribed by A. M. Shestopalov; L. A. Rodinovskaya; Yu. A. Sharanin; V. P. Litvinov
- Book ID
- 112447946
- Publisher
- Springer
- Year
- 1990
- Tongue
- English
- Weight
- 436 KB
- Volume
- 39
- Category
- Article
- ISSN
- 1573-9171
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π SIMILAR VOLUMES
Wittig reagents 2 react with furfiurylidenemalonitrile (la) und thienylidenemalonitrile (Ib) to give a mixture of products (6 and 7). Compound l b reacts with dialkyl phosphites (3) and trialkyl phosphites (4) to give the phosphonate 1:l adducts 9 and 12, respectively. Structures of the new products
The reactions of Ξ±,Ξ²-unsaturated nitriles (1, 9, 12) as bielectrophiles with aminoazoles (2, 4, 6) as binucleophiles were investigated. Acrylonitrile (1) reacts almost exclusively in a chemoselective Michael-type addition yielding the substituted azoles 3, 5 and 7, respectively. Cinnamonitriles 9a,b