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Regio- and Stereocontrolled Synthesis of 2d-Deoxy Lewisx Pentasaccharide

โœ Scribed by Yanyan Zhang; Dengxiang Dong; Huanhuan Qu; Matthieu Sollogoub; Yongmin Zhang


Book ID
102172257
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
444 KB
Volume
2011
Category
Article
ISSN
1434-193X

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AbstracL Deryrhro-Sphingosine (1) and phytosphingosine (2) have been efficiently synthesized from D-glucosamine by utilizing its whole carbon skeleton and functional groups. In this synthetic route, regioselective alkylation of the epoxy-tosylate 9 was achieved with a copper(I)-catalyzed Grignard re