Regeneration in the central nervous system
โ Scribed by Christine E Bandtlow
- Book ID
- 114253816
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 729 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0531-5565
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The factors inhibiting regeneration in the central nervous system (CNS) have been elaborated, debated, and studied for the past 70 years. Recent work has pointed to the fine balance that exists between repair and regeneration following CNS injury. Growth factors have featured prominently in this deb
## Abstract Reactive astrocytes are one of the main impediments for axonal regeneration in the central nervous system of mammals. Using mice KO for GFAP and vimentin, we show that reinnervation occurs after an hemisection of the spinal cord, mainly through sprouting of controlateral intact serotoni