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Refolding of ribonuclease A monitored by real-time photo-CIDNP NMR spectroscopy

✍ Scribed by Iain J. Day; Kiminori Maeda; Howard J. Paisley; K. Hun Mok; P. J. Hore

Book ID
106401622
Publisher
Springer Netherlands
Year
2009
Tongue
English
Weight
555 KB
Volume
44
Category
Article
ISSN
0925-2738

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It is shown that real-time 2D solid-state NMR can be used to obtain kinetic and structural information about the process of protein aggregation. In addition to the incorporation of kinetic information involving intermediate states, this approach can offer atom-specific resolution for all detectable