11q23-24 chromosome is a region containing frequent allelic loss (loss of heterozygosity; LOH) in human cancers. To examine cancer-related allelic loss in the region between D11S940 and APOC3, we used 17 polymorphic markers and allotyped 28 lung cancer-derived cell lines and their corresponding matc
Refined mapping of allele loss at chromosome 10q23-26 in prostate cancer
✍ Scribed by Barbara Leube; Matthias Drechsler; Kristina Mühlmann; Reinhold Schäfer; Wolfgang A. Schulz; Simon Santourlidis; Aristoteles Anastasiadis; Rolf Ackermann; Tapio Visakorpi; Wolfram Müller; Brigitte Royer-Pokora
- Book ID
- 118285882
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- English
- Weight
- 276 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0270-4137
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## Abstract A previous study of 18 primary or metastatic prostate cancers showed loss of genetic markers on chromosome 8; 10, or 16 in more than 50% of cases [Bergerheim USR et al. (1991) Genes Chromosom Cancer 3:215–220]. The small size and infiltrative nature of primary prostatic tumors have hind