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Redundant Pathways for Negative Feedback Regulation of Bile Acid Production

✍ Scribed by Li Wang; Yoon-Kwang Lee; Donnie Bundman; Yunqing Han; Sundararajah Thevananther; Chang-Soo Kim; Steven S Chua; Ping Wei; Richard A Heyman; Michael Karin; David D Moore


Book ID
117795196
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
443 KB
Volume
2
Category
Article
ISSN
1534-5807

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Bile acid–induced negative feedback regu
✍ Ezequiel Neimark; Frank Chen; Xiaoping Li; Benjamin L. Shneider πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 246 KB

Ileal expression of the apical sodium-dependent bile acid transporter (ASBT) in the rat is unaffected by bile salts, yet in the mouse it is under negative-feedback regulation. The bile acid responsiveness of human ASBT is unknown. The human ASBT promoter linked to a luciferase reporter was studied i