Reductive desulfonylation of phenyl sulfones by samarium(II) iodide-hexamethylphosphoric triamide
✍ Scribed by H. Künzer; M. Stahnke; G. Sauer; R. Wiechert
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- French
- Weight
- 163 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0040-4039
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Reductive Opening of Cyclopropylogous α-Hydroxy Aldehydes and Ketones by Samarium(II) Iodide. -The regioselectivity of the title reaction is found to be strongly dependant on the substitution pattern of the substrate. In several cases, a tandem cyclopropyl opening-deoxygenation reaction leads to γ-
## Samarium diiodide promotes under mild conditions, intramolecular reductive cyclisation of /3-chloro-substituted amides, and leads with an excellent diastereomeric excess and high yield to functionalked optically active cyclopropamls. We have recently reported that cyclopropanone hemiketal Is, r
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