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Reduction of the enterohepatic circulation of norethisterone by antibiotics in the rat: Correlation with changes in the gut flora

✍ Scribed by D.J. Back; A.M. Breckenridge; Francesca E. Crawford; Karen J. Cross; M.L'E. Orme; A. Percival; P.H. Rowe


Book ID
116001949
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
634 KB
Volume
13
Category
Article
ISSN
0022-4731

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The pharmacokinetics of two beta adrenoceptor blocking drugs, exaprolol and propranolol, in rats with interrupted enterohepatic circulation was studied. The tritium-labelled drugs were given intravenously to four groups of rats: control, bile-duct cannulated, bile-duct ligated, and pretreated with n