## Abstract ## Purpose To investigate the source of native low‐frequency fluctuations (LFF) in functional MRI (fMRI) signal. ## Materials and Methods Phase analysis was performed on tissue‐segmented fMRI data acquired at systematically varying sampling rates. ## Results LFF in fMRI signal were
Reduction of signal fluctuation in functional MRI using navigator echoes
✍ Scribed by Xiaoping Hu; Seong-Gi Kim
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 963 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0740-3194
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✦ Synopsis
Abstract
Functional magnetic resonance imaging is sensitive to signal fluctuations due to physiological motion and system instability. In this paper, motion‐related signal fluctuations are studied, and a method that uses navigator echoes to monitor and compensate for signal fluctuations in a gradient‐echo sequence is described. The technique acquires a “navigator” signal before the application of the phase‐encoding and readout gradients and corrects the phase of the subsequently acquired imaging data. This technique was implemented on a 4 Tesla whole body system and validated on normal volunteers. With this technique, temporal fluctuations in image intensity were substantially reduced and improved functional activation maps were obtained.
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