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Reduction of genistein clastogenicity in Chinese hamster V79 cells by daidzein and other flavonoids

โœ Scribed by Ronald D. Snyder; Peter J. Gillies


Book ID
117450216
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
387 KB
Volume
41
Category
Article
ISSN
0278-6915

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โœ Ronald D. Snyder ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 117 KB

Determination of the clastogenic potential of new chemical entities, particularly pharmaceuticals, is an important part of the overall safety assessment of such drugs. It is appreciated that clastogenicity can arise from perturbation of many different cellular processes distinct from direct DNA/drug