✦ LIBER ✦

Evaluation of the clastogenic, DNA intercalative, and topoisomerase II-interactive properties of bioflavonoids in Chinese hamster V79 cells

✍ Scribed by Ronald D. Snyder; Peter J. Gillies

Publisher: John Wiley and Sons
Year: 2002
Tongue: English
Weight: 177 KB
Volume: 40
Category: Article
ISSN: 0893-6692
DOI: 10.1002/em.10121

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Use of catalytic topoisomerase II inhibi

Use of catalytic topoisomerase II inhibitors to probe mechanisms of chemical-induced clastogenicity in Chinese hamster V79 cells

✍ Ronald D. Snyder 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 117 KB

Determination of the clastogenic potential of new chemical entities, particularly pharmaceuticals, is an important part of the overall safety assessment of such drugs. It is appreciated that clastogenicity can arise from perturbation of many different cellular processes distinct from direct DNA/drug

Analysis of the DNA damage induced by pr

Analysis of the DNA damage induced by praziquantel in V-79 Chinese hamster fibroblasts and human blood cells using the single-cell gel electrophoresis assay

✍ Luis A. Herrera; Mahara Valverde; Patricia Ostrosky-Wegman; Günther Speit; Emili 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 72 KB 👁 3 views

The analysis of the genotoxicity of praziquantel, an effective antihelminthic widely used in countries where parasitic infections are still serious public health problems, has been extensively performed using diverse in vitro and in vivo assays and endpoints. However, results are not conclusive, sin