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Reduction of dopaminergic degeneration and oxidative stress by inhibition of angiotensin converting enzyme in a MPTP model of parkinsonism

✍ Scribed by Ana Muñoz; Pablo Rey; Maria J. Guerra; Estefania Mendez-Alvarez; Ramon Soto-Otero; Jose L. Labandeira-Garcia


Book ID
116784550
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
495 KB
Volume
51
Category
Article
ISSN
0028-3908

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Angiotensin-converting enzyme inhibition
✍ A. Lopez-Real; P. Rey; R. Soto-Otero; E. Mendez-Alvarez; J.L. Labandeira-Garcia 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 274 KB 👁 1 views

## Abstract It is now established that the brain possesses a local renin‐angiotensin system and that angiotensin II exerts multiple actions in the nervous system, including regulation of striatal dopamine release. Furthermore, angiotensin activates NADPH‐dependent oxidases, which are a major source