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Reduction of benzo(a)pyrene mutagenicity by dihydrodiol dehydrogenase

✍ Scribed by GLATT, H. R.; VOGEL, K.; BENTLEY, P.; OESCH, F.


Book ID
109712922
Publisher
Nature Publishing Group
Year
1979
Tongue
English
Weight
257 KB
Volume
277
Category
Article
ISSN
0028-0836

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Chlorophyllin (CHL), a water soluble derivative of the green pigment chlorophyll, was evaluated for its antimutagenic activity towards benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide (BPDE). CHL suppressed dose-dependently the formation of 8-azaguanine-resistant mutant colonies in Salmonella typhimurium