A new and practical method for the reduction of 2,1,3-benzothiadiazoles to 1,2-benzenediamines with magnesium and methanol is described. Sensitive functional groups such as bromo, chloro, cyano, and ester are well tolerated under these new conditions.
โฆ LIBER โฆ
Reduction as a probe for benzothiirene intermediates: Thermal and photochemical decomposition of 1,2,3 -benzothiadiazoles.
โ Scribed by R.C White; J Scoby; T.D Roberts
- Publisher
- Elsevier Science
- Year
- 1979
- Tongue
- French
- Weight
- 193 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0040-4039
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## Abstract Palladiumโcatalyzed amination of 7โbromoโ4โmethylโ2,1,3โbenzothiadiazole (**7**) with benzophenone imine as an ammonia equivalent is described as a new, safe and practical alternative to nitration for the synthesis of 7โaminoโ4โmethylโ2,1,3โbenzothiadiazole (**1**) in high yield. This m