Reducing nephrotoxicity in pediatric liver transplant recipients with low-dose tacrolimus and mycophenolate mofetil
✍ Scribed by N.R. Barshes; I. Chang; I.W. Udell; T.C. Lee; C.A. O’Mahony; S.J. Karpen; B.A. Carter; J.A. Goss
- Book ID
- 116702256
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 45 KB
- Volume
- 130
- Category
- Article
- ISSN
- 0022-4804
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The pharmacokinetics of mycophenolate mofetil (MMF) in liver transplant recipients may change because of pharmacokinetic interactions with coadministered immunosuppressants or because changes in the enterohepatic anatomy may affect biotransformation of MMF to mycophenolic acid (MPA) and enterohepati
There are few pharmacokinetic data for mycophenolate mofetil (MMF) when used in combination with cyclosporine (CsA) in pediatric liver transplant recipients. The aim of this study was to assess the pharmacokinetics of MMF in stable pediatric liver transplant patients and estimate the dose of MMF req