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Reducing inflammation decreases secondary degeneration and functional deficit after spinal cord injury

✍ Scribed by Rafael Gonzalez; Janette Glaser; Michael T Liu; Thomas E Lane; Hans S Keirstead


Book ID
117101010
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
386 KB
Volume
184
Category
Article
ISSN
0014-4886

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FK506 reduces tissue damage and prevents
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## Abstract We examined the efficacy of FK506 in reducing tissue damage after spinal cord injury in comparison to methylprednisolone (MP) treatment. Rats were subjected to a photochemical injury (T8) and were given a bolus of MP (30 mg/kg), FK506 (2 mg/kg), or saline. An additional group received a