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Reduced penetrance and variable expressivity of familial thoracic aortic aneurysms/dissections

✍ Scribed by Dianna M. Milewicz; Hua Chen; Eun-Sook Park; Elizabeth M. Petty; Hedayatollah Zaghi; G.Shashidhar Pai; Marcia Willing; Vasant Patel


Book ID
113979708
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
89 KB
Volume
82
Category
Article
ISSN
0002-9149

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Genetic basis of thoracic aortic aneurys
✍ Hariyadarshi Pannu; Van Tran-Fadulu; Dianna M. Milewicz πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 175 KB

## Abstract Ascending thoracic aortic aneurysms leading to type A dissections (TAAD) can occur in association with a genetic syndrome, such as Marfan syndrome (MFS), or as an autosomal dominant disorder in the absence of syndromic features, termed familial TAAD. Familial TAAD demonstrates genetic h