Familial Thoracic Aortic Aneurysms and Dissections—Incidence, Modes of Inheritance, and Phenotypic Patterns
✍ Scribed by Gonzalo Albornoz; Michael A. Coady; Michele Roberts; Ryan R. Davies; Maryann Tranquilli; John A. Rizzo; John A. Elefteriades
- Book ID
- 116262140
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 227 KB
- Volume
- 82
- Category
- Article
- ISSN
- 0003-4975
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Ascending thoracic aortic aneurysms leading to type A dissections (TAAD) can occur in association with a genetic syndrome, such as Marfan syndrome (MFS), or as an autosomal dominant disorder in the absence of syndromic features, termed familial TAAD. Familial TAAD demonstrates genetic h
## Abstract A genetic predisposition for thoracic aortic aneurysms and dissections (TAAD) can be inherited in an autosomal dominant manner with decreased penetrance and variable expression. Four genes identified to date for familial TAAD account for approximately 20% of the heritable predisposition