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Reduced folate carrier A80G polymorphism and susceptibility to neural tube defects: A meta-analysis

✍ Scribed by Hai-Gang Wang; Jia-Li Wang; Jian Zhang; Li-Xia Zhao; Guang-Xi Zhai; Yu-zhu Xiang; Ping Chang

Book ID: 119241260
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 481 KB
Volume: 510
Category: Article
ISSN: 0378-1119
DOI: 10.1016/j.gene.2012.02.020

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## Abstract ## BACKGROUND There is a considerable body of data demonstrating that periconceptional supplementation of folic acid can prevent a significant proportion of neural tube defects (NTDs). At present, the mechanism by which folic acid exerts its beneficial effect remains unknown. Folate tr