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Reduced folate carrier polymorphism (80A→G) and neural tube defects

✍ Scribed by De Marco, Patrizia; Calevo, Maria Grazia; Moroni, Anna; Merello, Elisa; Raso, Alessandro; Finnell, Richard H.; Zhu, Huiping; Andreussi, Luciano; Cama, Armando; Capra, Valeria

Book ID
110025363
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
105 KB
Volume
11
Category
Article
ISSN
1018-4813

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## Abstract ## BACKGROUND There is a considerable body of data demonstrating that periconceptional supplementation of folic acid can prevent a significant proportion of neural tube defects (NTDs). At present, the mechanism by which folic acid exerts its beneficial effect remains unknown. Folate tr