Reduced expression of the E-cadherin gene and its aberrant DNA methylation in hamster pancreatic tumors
β Scribed by Kyoko Shimizu; Madoka Hanaoka; Ayumi Kato; Hiromasa Fujii; Kanya Honoki; Toshifumi Tsujiuchi
- Book ID
- 116291168
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 245 KB
- Volume
- 336
- Category
- Article
- ISSN
- 0006-291X
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## Abstract ## BACKGROUND. Lung cancer is the leading cause of cancer deaths worldwide. The epigenetic inactivation of certain genes by aberrant promoter methylation plays an important role in the pathogenesis of lung cancer. In addition, DNA hypermethylation is an extremely promising cancer marke