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Reduced expression of p27Kip1 correlates with an early stage of cancer invasion in oral squamous cell carcinoma

โœ Scribed by Yasusei Kudo; Takashi Takata; Ikuko Ogawa; Ming Zhao; Sunao Sato; Toshitsugu Takekoshi; Mutsumi Miyauchi; Hiromasa Nikai

Book ID
117469772
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
328 KB
Volume
151
Category
Article
ISSN
0304-3835

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Reduced expression of cyclin-dependent kinase inhibitor p27Kip1 is an indicator of malignant behavior in oral squamous cell carcinoma
โœ Yasusei Kudo; Takashi Takata; Wataru Yasui; Ikuko Ogawa; Mutsumi Miyauchi; Toshi ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 199 KB ๐Ÿ‘ 2 views

Reduced expression of the cyclin-dependent kinase inhibitor p27 Kip1 has been reported to correlate with poor survival in cohorts of breast and colorectal carcinoma patients. Posttranslational ubiquitin-mediated proteasomal proteolysis is related to p27 Kip1 protein levels. However, to the authors'