Reduced expression of cyclin-dependent k
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Yasusei Kudo; Takashi Takata; Wataru Yasui; Ikuko Ogawa; Mutsumi Miyauchi; Toshi
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Article
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1998
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John Wiley and Sons
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English
⚖ 199 KB
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Reduced expression of the cyclin-dependent kinase inhibitor p27 Kip1 has been reported to correlate with poor survival in cohorts of breast and colorectal carcinoma patients. Posttranslational ubiquitin-mediated proteasomal proteolysis is related to p27 Kip1 protein levels. However, to the authors'