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Reduced expression of cyclin-dependent kinase inhibitor p27Kipl is an indicator of malignant behavior in oral squamous cell carcinoma


Book ID
117610332
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
220 KB
Volume
29
Category
Article
ISSN
0901-5027

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Reduced expression of cyclin-dependent k
✍ Yasusei Kudo; Takashi Takata; Wataru Yasui; Ikuko Ogawa; Mutsumi Miyauchi; Toshi 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 199 KB 👁 2 views

Reduced expression of the cyclin-dependent kinase inhibitor p27 Kip1 has been reported to correlate with poor survival in cohorts of breast and colorectal carcinoma patients. Posttranslational ubiquitin-mediated proteasomal proteolysis is related to p27 Kip1 protein levels. However, to the authors'