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Cyclin-dependent kinase inhibitor p27Kip1 expression in transitional cell carcinoma of renal pelvis and ureter

โœ Scribed by Mistunobu Masuda; Yasuo Takano; Masayuki Iki; Kazuhide Makiyama; Ichiro Ikeda; Sumio Noguchi; Yukio Hasegawa; Masahiko Hosaka


Book ID
117469742
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
807 KB
Volume
150
Category
Article
ISSN
0304-3835

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Reduced expression of the cyclin-dependent kinase inhibitor p27 Kip1 has been reported to correlate with poor survival in cohorts of breast and colorectal carcinoma patients. Posttranslational ubiquitin-mediated proteasomal proteolysis is related to p27 Kip1 protein levels. However, to the authors'