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Key role of the cyclin-dependent kinase inhibitor p27kip1 for embryonal carcinoma cell survival and differentiation

✍ Scribed by Baldassarre, Gustavo; Barone, Maria Vittoria; Belletti, Barbara; Sandomenico, Claudia; Bruni, Paola; Spiezia, Stefania; Boccia, Angelo; Vento, Maria Teresa; Romano, Annunciata; Pepe, Stefano


Book ID
110062417
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
742 KB
Volume
18
Category
Article
ISSN
0950-9232

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Reduced expression of cyclin-dependent k
✍ Yasusei Kudo; Takashi Takata; Wataru Yasui; Ikuko Ogawa; Mutsumi Miyauchi; Toshi πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 199 KB πŸ‘ 2 views

Reduced expression of the cyclin-dependent kinase inhibitor p27 Kip1 has been reported to correlate with poor survival in cohorts of breast and colorectal carcinoma patients. Posttranslational ubiquitin-mediated proteasomal proteolysis is related to p27 Kip1 protein levels. However, to the authors'